COVID-19: Leave politics out of practicing medicine

Practicing medicine Abbreviations

The promising clinical data for the first orally active phosphodiesterase inhibitor, sildenafil (Viagra), for treating male erectile dysfunction (ED) boosted research activities into the physiology of the erectile mechanism. Peripheral intracellular signal transduction in the penis as well as central brain and spinal cord pathways controlling penile erection have been researched. The results pr...

The Leave - one - out

For-Profit Hospitals Out of Business? Financial Sustainability During the COVID-19 Epidemic Emergency Response

This perspective argues that for-profit hospitals will be heavily affected by epidemic crises, including the current coronavirus disease 2019 (COVID-19) outbreak. Policy-makers should be aware that for-profit hospitals in particular are likely to face financial distress. The suspension of all non-urgent elective surgery and the relegation of market-based mechanisms that...

Practicing Evidence-Based Stroke Medicine.

The practice of evidence-based medicine depends on several steps: a basic science derived understanding of disease pathophysiology, epidemiological research, and the results of well-conducted and appropriately analyzed randomized clinical trials (RCTs). The approval of new therapies by regulatory agencies is also based largely on RCT determination of the safety and therapeutic efficacy of drugs...

The Leave-One-Out Kernel

Recently, several attempts have been made for deriving datadependent kernels from distribution estimates with parametric models (e.g. the Fisher kernel). In this paper, we propose a new kernel derived from any distribution estimators, parametric or nonparametric. This kernel is called the Leave-one-out kernel (i.e. LOO kernel), because the leave-one-out process plays an important role to comput...